Astros vs Angels Picks and Prediction – 6/22/2025

This Saturday, Brandon Walter takes the mound for the Astros against José Soriano and the Angels. Get our free MLB Picks all season long! Houston is coming off a 6-4 loss to the Athletics, while the Angels dropped a 7-3 decision to the Yankees. Both clubs will look to rebound in this divisional battle at Angel Stadium.

Walter has flashed solid stuff in his limited action, relying heavily on his cutter and changeup. He’ll be looking to bounce back and keep Houston’s strong rotation rolling. The Astros’ offense, led by Kyle Tucker and Yordan Álvarez, remains dangerous despite some inconsistency in recent games.

On the other side, Soriano will try to regain command after giving up too many base runners in his last outing. His high-velocity sinker makes him a tough assignment if he’s dialed in. Offensively, the Angels are led by Logan O’Hoppe and a supporting cast trying to cover for the absence of big bats.

Expect this to be a close, low-scoring contest with a couple of timely hits making the difference. Houston’s bullpen has been sharper of late and could be the edge in this one, as long as their batters show up and execute.

Houston enters this matchup looking to shake off Thursday’s loss and stay in the division race. With Brandon Walter on the mound and timely hitting, they’ll have a slight edge. The Angels struggle with consistency, and José Soriano’s control could be an issue. Take the Astros to win this one on the road. Final Score Prediction, Houston Astros win 4-2.