Astros vs Royals Picks and Prediction – 4/26/2025

By: Cameron Ross |

Last Updated: 04/25/2025 at 11:44 PM ET

Houston Astros at Kansas City Royals 04/26/25 - MLB Picks & Predictions
Game Start: 4/26/2025, 11:10 PM UTC
Latest Odds: HOU -142 ; O/U 7.9

Astros vs Royals Prediction

The Houston Astros stay on the road Saturday with a game in Kansas City for game two of three against the Royals. Houston has 13 wins and 11 losses on the year coming into this series after winning for the last five including three in a row after a three-game sweep against the Toronto Blue Jays. Offensively, Houston has been mediocre this season with a .236 batting average having scored 92 runs on 186 hits. The Houston pitching has been solid however with a 3.26 team ERA. Stay in the action with our MLB Picks.

Jose Altuve leads the Houston offense this season with a .293 batting average. Isaac Paredes has a .233 batting average and has boasted a team leading four home runs this season. Jeremy Pena has a .253 batting average and Jake Meyers has a .265 batting average. Big man Yordan Alvarez is tied with Isaac Paredes leading the way with 13 RBI's this season.

The Kansas City Royals stay home coming into the weekend with twelve wins and 14 losses on the year riding a 4 game-winning streak following a three-game sweep of the Colorado Rockies. Offensively Kansas City has a .221 team batting average after scoring 84 runs on 189 hits this season. The Kansas City power has been lackluster however with only twelve home runs and a .320 slugging percentage.

Bobby Witt Jr. leads Kansas City this season with a .303 batting average. Maikel Garcia has been vital as well for the team this season with a .286 batting average. Salvador Perez, Bobby Witt Jr, Vinny Pasquantino, and Maikell Garcia all lead Kansas City this season with two home runs apiece. Vinny Pasquantino leads the team with 15 RBIs across 25 games played.

Astros vs Royals Pick Analysis

Despite being on the road the Astros have the edge in this game. Look for Houston to do the work on both sides of the plate leading to the win. Houston has the better pitcher the mound and that will carry them to the win. Final Score Prediction, Houston Astros win 7-3.

Our Free MLB Pick for Kansas City Royals vs Houston Astros

Houston Astros -142