Astros vs Royals Picks and Prediction – 4/25/2025

The Houston Astros open a three-game series on the road Friday versus the Kansas City Royals. Houston is 13-11 following a 3-1 victory over the Toronto Blue Jays on Wednesday, completing a three-game sweep of Toronto. Christian Walker homered for the Astros. Houston is tied for second in the American League West with Seattle, one game behind first-place Texas. Keep up to date with all the MLB action with our MLB picks.

Jose Altuve is batting .293 with 29 hits to lead Houston in both categories. Isaac Paredes is the leader in home runs with four and on-base percentage at .337. Yordan Alvarez is the leader in RBI with 13. Houston is batting .236 with a .349 slugging percentage. On Friday, the Houston Astros will send Hayden Wesneski to the mound. The right-hander is 1-1 with a 3.91 ERA, 25 Ks, and 4 BBs.

The Kansas City Royals improved to 10-14 with a 4-3 victory over the Colorado Rockies on Tuesday. The Royals and Rockies game scheduled for Wednesday was postponed due to rain and will be made up as part of a doubleheader on Thursday. Kansas City is third in the American League Central, 4 ½ games behind the first-place Detroit Tigers.

Bobby Witt Jr is batting .308 with 28 hits and an on-base percentage of .381 to lead Kansas City in the three categories. Salvador Perez is one of four players for Kansas City with two home runs. Vinnie Pasquantino is the leader in RBI with 14. On Friday, the Kansas City Royals will send Seth Lugo to the mound. The right-hander is 1-3 with a 3.90 ERA, 21 Ks, and 11 BBs.

Houston has won five of its last six and will have an advantage as the Astros have Wednesday off, while Kansas City must play a doubleheader versus Colorado. Houston starter Hayden Wesneski has had two consecutive average outings, allowing five runs across 11 innings. Kansas City starter Seth Lugo has been hit hard in two consecutive outings, allowing seven runs on 12 hits across 13.1 innings. Final Score Prediction: Houston Astros win 6-2.