Astros vs Guardians Picks and Prediction – 6/8/2025

The Houston Astros complete a three-game series on the road Sunday versus the Cleveland Guardians. Houston improved to 35-28 following Friday’s 4-2 victory over Cleveland in the opening game of the series. Houston has won two straight and four of its last five. The Astros lead the American League West by 2 ½ games over the Seattle Mariners. Keep up to date with all the MLB action with our MLB predictions.

Jeremy Pena is batting .324 to lead Houston and has team highs in hits with 78 and on-base percentage at .382. Isaac Paredes is the leader in home runs with 14 and in RBI with 37. Houston is batting .253 with a .391 slugging percentage. The Houston Astros have not yet announced a starting pitcher for Sunday's final game of a three-game series on the road versus Cleveland.

The Cleveland Guardians dropped to 33-29 following Friday’s two-run loss to the Houston Astros. Cleveland has lost two straight and three of the last four. The Guardians have struggled at the plate, as Cleveland is 23rd in slugging percentage, while 24th in both on-base percentage and batting average. Cleveland trails first-place Detroit by 7 ½ games in the AL Central.

Jose Ramirez is batting .329 with 11 home runs, 29 RBI, 75 hits, and a .382 on-base percentage to lead Cleveland in the five categories. Kyle Manzardo is tied for the lead in home runs with 11. Cleveland is batting .234 with a .378 slugging percentage. On Sunday, the Cleveland Guardians will send Tanner Bibee to the mound. The right-hander is 4-6 with a 3.89 ERA, 56 Ks, and 23 BBs.

The Houston Astros have won four of the last five and have dominated Cleveland, winning eight of the last nine versus the Guardians. Cleveland has lost seven of its last 10 played during June. The Guardians have dropped six of the last nine versus an opponent from the American League West. Cleveland starter Tanner Bibee has been hit hard in two consecutive outings, allowing seven runs on 11 hits across 11.1 innings. Final Score Prediction: Houston Astros win 6-3.