Astros vs White Sox Picks and Prediction – 5/3/2025

In Saturday afternoon MLB action, the Houston Astros and the Chicago White Sox will continue their weekend series from Rate Field. Be ready for the baseball season with all of our MLB predictions. The Astros (16-15) are three games below .500 on the road and are sitting in third place in the AL West Division standings. Last night, Houston C Yainer Diaz went 3-for-4 with a home run and scored twice during a 7-3 road loss.

Twenty-six year old righty Hunter Brown (4-1 1.22 ERA) is making a strong case to make his first All-Star appearance. The Astros have won Brown’s last three starts and he has allowed just one run over his last 25 innings. 

The Chicago White Sox have dropped ten of their first 16 home games and own the worst overall record in the American League. During Friday’s home victory, C Edgar Quero drove in a pair of runs and OF Luis Robert added his fifth home run of the year to spark the Chicago offense. SP Jonathan Cannon (2-3) allowed two runs in six innings to earn the win for the White Sox (9-23). 

Twenty-eight year old righty Davis Martin (1-3 3.24 ERA) has been one of the lone bright spots for the White Sox. In his last start, Martin fired six shutout frames and fanned five batters during a 3-2 road loss against the Athletics. 

Houston SP Lance McCullers Jr. (forearm) will be activated from the 15-day injured list to start Sunday’s series finale. Through 31 games, Houston ranks 23rd in OPS and 23rd in runs scored. For the season, Chicago ranks 27th in OPS and 25th in runs scored. Take the under. Final Score Prediction, Houston Astros win 4-2.