Astros vs White Sox Picks and Prediction – 5/2/2025

By: Cameron Ross |

Last Updated: 05/01/2025 at 7:53 PM ET

Houston Astros at Chicago White Sox 05/02/25 - MLB Picks & Predictions
Game Start: 5/2/2025, 11:40 PM UTC
Latest Odds: HOU -235 ; O/U 7.5

Astros vs White Sox Prediction

The Houston Astros will be on the road Friday for game one of three in Chicago against the White Sox. Houston has sixteen wins and fourteen losses this season following a three run losses the Detroit Tigers in their last outing to end a three-game winning streak. Offensively Houston has a .236 batting average having scored 117 runs on 233 hits this season. The Houston pitching has been the team's biggest strength this year with a 3.23 team ERA. Stay in the action with our MLB Picks.

Jeremy Pena leads the Houston offense this season with a .282 batting average. Isaac Paredes has a .252 batting average and Jake Meyers has a .250 batting average this season. Jose Altuve, Isaac Paredes, Jeremy Pena, and Christian Walker are all tied for the top spot on the roster leading the team with four home runs apiece. Yordan Alvarez also leads Houston this season with eighteen RBIs in 28 games played.

The Chicago White Sox stay on their home field Friday as one of the worst teams in baseball 16 games below .500 on the year after losing four of the last five including three in a row. Offensively Chicago was terrible with .211 team batting average. The White Sox have scored just 101 runs on 206 hits this season. The Chicago pitching is just as bad as they're hitting with a 4.19 team ERA.

Lenyn Sosa is the offensive leader this season for Chicago with a .269 batting average. Brooks Baldwin has a .241 batting average and leads Chicago with 13 RBI's this season. Andrew Benintendi has a .227 batting average and Miguel Vargas has shipped in heavily this season with a .219 batting average. Benintendi also leads the team this season with five home runs through 21 games played.

Astros vs White Sox Pick Analysis

The White Sox are one of the worst teams in baseball and their struggles will continue Friday against Houston. The Astros have the stronger offense and the better overall arm on the mound to lead them in this game. Take the Astros Friday to kick off the weekend with a road win in Chicago. Final Score Prediction, Houston Astros win 6-1.

Our Free MLB Pick for Chicago White Sox vs Houston Astros

Houston Astros