Tigers vs Rays Picks and Prediction – 6/21/2025

By: Eddie Kline |

Last Updated: 06/20/2025 at 11:19 PM ET

Detroit Tigers at Tampa Bay Rays 06/21/25 - MLB Picks & Predictions
Game Start: 6/21/2025, 4:10 PM UTC
Latest Odds: TAM -125 ; O/U 9

Tigers vs Rays Prediction

The Saturday MLB schedule will get underway with a matinee between the Detroit Tigers and the Tampa Bay Rays from Steinbrenner Field. Be ready for the baseball season with all of our MLB predictions. The Tigers (48-29) are five games above .500 on the road and own the best overall record in the majors. Last night, Detroit OF Riley Greene homered twice and drove in four runs during an 14-8 road loss against Tampa Bay. 

Twenty-seven year old righty Sawyer Gipson-Long (0-0 3.97 ERA) will make his second start of the year for the Tigers. In his first start, Gibson-Long lasted just three plus innings and gave up three runs during a 5-4 road victory against Chicago. 

The Tampa Bay Rays have won seven of their last 11 games and trail AL East Division leading New York by two games. During Friday’s home victory, leadoff hitter Yandy Diaz went 3-for-4 with two long balls to power the Tampa Bay offense. C Matt Thaiss went 3-for-4 with four RBIs for the Rays (42-34), who improved to 26-22 at home. 

The Rays will counter with twenty-seven year old righty Ryan Pepiot (4-6 3.11 ERA) on Saturday. Last time out, Pepiot (8 IP) allowed one run and retired 11 batters by strikes during a 7-1 home victory versus Baltimore.

Tigers vs Rays Pick Analysis

Tampa Bay SP Shane McClanahan (triceps) should start throwing off a mound soon and plans to return in about a month. Through 77 games, Detroit ranks 6th in OPS and 5th in runs scored. For the season, Tampa Bay ranks 14th in OPS and 10th in runs scored. Take the over. Final Score Prediction, Tampa Bay Rays win 6-5.

Our Free MLB Pick for Tampa Bay Rays vs Detroit Tigers

OVER 9