Tigers vs Cardinals Picks and Prediction – 5/19/2025

The Detroit Tigers open a three-game series on the road Monday versus the St Louis Cardinals. Detroit dropped to 30-16 following its 2-1 loss to the Toronto Blue Jays on Saturday. The loss snapped a four-game winning streak by the Tigers. Detroit is leading the American League Central by four games over the second-place Minnesota Twins. Keep up to date with all the MLB action with our MLB previews.

Gleyber Torres is batting .295 to lead Detroit, and Riley Greene is the leader in hits with 47. Spencer Torkelson is the leader in home runs with 12 and RBI with 35, while Zach McKinstry is the leader in on-base percentage at .367. Detroit is batting .259 with a .425 slugging percentage. On Monday, Detroit will send Keider Montero to the mound. The right-hander is 1-1 with a 4.68 ERA, 18 Ks, and 11 BBs. 

The St Louis Cardinals improved to 26-20 following Saturday’s 1-0 victory over the Kansas City Royals. Jordan Walker hit a solo home run for St Louis, and Miles Mikolas threw six shutout innings. St Louis has won three straight and 12 of the last 13. The Cardinals are just one game behind the first-place Chicago Cubs in the National League Central.

Brandan Donovan is batting .316 with 54 hits and a .376 on-base percentage to lead St. Louis in the three categories. Lars Nootbaar is the leader in home runs with seven, and Willson Contreras is the leader in RBI with 26. St. Louis is batting .261 with a .403 slugging percentage. On Monday, St. Louis will send Sonny Gray to the mound. The right-hander is 4-1 with a 4.50 ERA, 51 Ks, and 12 BBs.

Detroit has won four of its last six overall, and the Tigers have won five of the last six played on the road. Detroit starter Keider Montero gave up three runs on five hits across 3.1 innings in a relief appearance last Tuesday. St Louis starter Sonny Gray is coming off a poor outing, in which the right-hander allowed 7 runs on eight hits across 3.2 innings. Look for plenty of runs in this matchup, and therefore the play here is OVER. Final Score Prediction: Detroit Tigers win but our best play is OVER 7-5.