Tigers vs Astros Picks and Prediction – 4/30/2025

By: Eddie Kline |

Last Updated: 04/29/2025 at 11:30 PM ET

Detroit Tigers at Houston Astros 04/30/25 - MLB Picks & Predictions
Game Start: 4/30/2025, 6:10 PM UTC
Latest Odds: HOU -138 ; O/U 8.5

Tigers vs Astros Prediction

The Wednesday MLB schedule will get underway with a matinee between the Detroit Tigers and the Houston Astros from Daikin Park. Be ready for the baseball season with all of our MLB predictions. The Tigers (18-12) are four games below .500 on the road and hold a two-game lead over Cleveland for the top spot in the AL Central Division. Last night, Detroit OF Kerry Carpenter hit his seventh home run of the year and 2B Gleyber Torres added a two-run shot during a 6-2 road loss against Houston. 

Rookie right-hander Jackson Jobe (2-0 2.70 ERA) will make his fifth career major league start for the Tigers. Last time out, Jobe (5 IP) allowed one run and struck out five batters during a 7-3 home victory versus Kansas City. 

The Houston Astros have won 11 of their first 17 home games and trail Seattle by a half-game for first place in the AL West Division. On Tuesday, Houston took the lead for good in the sixth inning on a two-run single from C Yainer Diaz. 1B Christian Walker went 2-for-3 with a run scored for the Astros, who improved to 16-13 overall.

The Astros will counter with twenty-seven year old righty Hayden Wesneski (1-2 3.86 ERA) on Wednesday. Through 28 innings of work, Wesneski has retired 26 batters by strikes and owns a sparkling 1.00 WHIP.

Tigers vs Astros Pick Analysis

Houston SP Cristian Javier (elbow) has been transferred to the 60-day injured list and is not eligible to return until July 20th. Through 30 games, Detroit ranks 12th in OPS and 22nd in runs scored. For the season, Houston ranks 24th in OPS and 11th in runs scored. Take the Tigers to win on the road. Final Score Prediction, Detroit Tigers win 5-3.

Our Free MLB Pick for Houston Astros vs Detroit Tigers

Detroit Tigers +118