Tigers vs Astros Picks and Prediction – 4/29/2025

By: David Anicetti |

Last Updated: 04/27/2025 at 8:26 PM ET

Detroit Tigers at Houston Astros 04/28/25 - MLB Picks & Predictions
Game Start: 4/29/2025, 12:10 AM UTC
Latest Odds: DET -115 ; O/U 8

Tigers vs Astros Prediction

The Detroit Tigers open a three-game series on the road Monday versus the Houston Astros. Detroit is 17-10 following its 6-2 victory over the Baltimore Orioles on Saturday. Detroit has won each of the first two games of its series with Baltimore, which concludes on Sunday. The Tigers are first in the American League Central, 1 ½ games ahead of the Cleveland Guardians. Keep up to date with all the MLB action with our MLB picks.

Zach McKinstry is batting .325 with 26 hits and an on-base percentage of .433 to lead the three categories. Spencer Torkelson is the leader in home runs with eight and RBI with 24. Detroit is batting .245 with a .388 slugging percentage. On Monday, the Detroit Tigers will send Jack Flaherty to the mound. The right-hander is 1-2 with a 2.63 ERA, 34 Ks, and 9 BBs.

The Houston Astros dropped to 13-13 following Saturday’s 2-0 loss to the Kansas City Royals. Houston has lost each of the first two games of its three-game series with Kansas City by the same score of 2-0. The Astros have won five of the last eight, but trail first-place co-leaders Seattle and Texas by 1 ½ games in the American League West.

Jose Altuve is batting .274 to lead Houston and has a team-high 29 hits. Isaac Paredes is the leader in home runs with four and on-base percentage at .348. Yordan Alvarez is the leader in RBI with 13. Houston is batting .230 with a .338 slugging percentage. On Monday, Houston will send Ronel Blanco to the mound. The right-hander is 2-2 with a 5.01 ERA, 20 Ks, and 12 BBs.

Tigers vs Astros Pick Analysis

Detroit will win on the road Monday when visiting Houston, but the play here is UNDER. The UNDER has cashed in four of Detroit’s last five and each of Houston’s last seven. Detroit starter Jack Flaherty has allowed five runs on 14 hits across the last 10.2 innings in the last two outings. Houston starter Ronel Blanco has allowed four runs on seven hits across the last 11.2 innings. Final Score Prediction: Detroit Tigers win, but our best play is UNDER 4-2.

Our Free MLB Pick for Houston Astros vs Detroit Tigers

Under 8