Guardians vs Giants Picks and Prediction – 6/19/2025

By: Cameron Ross |

Last Updated: 06/18/2025 at 8:25 PM ET

Cleveland Guardians at San Francisco Giants 06/19/25 - MLB Picks & Predictions
Game Start: 6/19/2025, 8:05 PM UTC
Latest Odds: SFG -168 ; O/U 7

Guardians vs Giants Prediction

The Cleveland Guardians remain on the road Thursday night for another game in San Francisco against the Giants. Cleveland has 36 wins and 35 losses this season, following a win in Game 1 of this series to end a three-game skid. Offensively Cleveland has been mediocre this season. With a .231 team batting average, the Guardians have scored 233 runs on 534 total hits this year. The Cleveland bullpen has been top-tier however, with a 3.96 team ERA. Stay on the action with our MLB Picks.

Jose Ramirez leads the Cleveland offense this season with a .319 batting average, thirteen home runs, and 83 hits. Steven Kwan has a .298 batting average and Gabriel Arias has a .239 batting average. Carlos Santana has a .248 batting average to go along with a team leading 35 RBI's this season.

The San Francisco Giants remain on their home field Thursday with 41 wins and 32 losses this season having dropped four of the last five including three in a row. Offensively San Francisco has a .233 team batting average having scored 311 runs on 561 hits. The San Francisco bullpen is one of the best in baseball with a 3.27 team ERA this year.

Helliot Ramos leads the San Francisco offense this season with a .285 batting average and 77 hits. Willie Adames has a .206 batting average, while Jung Hoo Lee has a .265 batting average. Matt Chapman has a .243 batting average and leads San Francisco this season with 12 home runs. Wilmer Flores is a .255 batting average to go along with the team leading 51 RBIs in 71 games played. Dominic Smith has a .325 batting average for San Francisco this season but has played in just 12 total games.

Guardians vs Giants Pick Analysis

Both teams are playing well this year, but the Giants will have the edge despite the recent skid. Look for San Francisco to do the work on both sides to overpower Cleveland. The Giants are stronger offensively and have the better pitcher on the mound. Take the Giants Thursday to end their recent skid with a win at home. Final Score Prediction, San Francisco Giants win 8-3.

Our Free MLB Pick for San Francisco Giants vs Cleveland Guardians

San Francisco Giants -168