Guardians vs Padres Picks and Prediction – 4/2/2025

The Cleveland Guardians will be returning to Petco Park on Tuesday, where they will take on the San Diego Padres. Get the rest of our free MLB picks here! The Cleveland Guardians are ranked 19th according to ESPN in the preseason rankings. Cleveland has been successful playing in San Diego as they are only 3-2 in the last five games played at Petco Park. Logan Allen is headed to the mound for the Guardians, he gave up 5 runs in 3 innings pitched against the Padres in the last start against them. Cleveland's bullpen is ranked 7th in preseason rankings. Kyle Manzardo leads the Guardians this season with a .455 batting average, 2 home runs, and 6 RBI. 

The San Diego Padres are ranked 10th according to ESPN in the preseason rankings. The Padres won the last two games they played against Cleveland. Michael King will be San Diego’s starting pitcher on Tuesday, he has beaten the Guardians in his last three starts against them. San Diego has the 16th best bullpen in preseason rankings. Jackson Merrill leads the Padres this season with a .556 batting average and 4 RBI.

The Cleveland Guardians have lost the last two games against the Padres. Guardians starting pitcher Logan Allen has given up quite a few hits and runs over his last five starts. San Diego has been playing well as they are 4-0 on the year. Michael King has pitched well against the Guardians winning his last three starts against Cleveland and will lead the Padres to a strong start in this matchup. The Padres will get some timely hitting and get the job done at home on Tuesday night. Final Score Prediction, San Diego Padres win 4-3.