Guardians vs Yankees Picks and Prediction – 6/4/2025

The Cleveland Guardians play the second game of a three-game series on the road Wednesday versus the New York Yankees. Cleveland is 32-26 and defeated the Los Angeles Angels 4-2 Sunday. Jose Ramirez hit a home run, and Gavin Williams gave up one hit across 6.2 innings. Cleveland is second in the American League Central, 6 ½ games behind the first-place Detroit Tigers. Keep up to date with all the MLB action with our MLB picks.

Jose Ramirez is batting .327 with 11 home runs, 29 RBI, and an on-base percentage of .384 to lead Cleveland in the four categories. Steven Kwan is the leader in hits with 70. Cleveland is batting .234 with a slugging percentage of .308. On Wednesday, the Cleveland Guardians will send Luis Ortiz to the mound. The right-hander is 2-6 with a 4.40 ERA, 64 Ks, and 30 BBs.

The New York Yankees improved to 36-22 following Sunday’s 7-3 victory over the Los Angeles Dodgers, avoiding a sweep after losing each of the first two games of that series. New York has won six of the last eight. New York is expected to place closer Luke Weaver on the injured list after the right-hander injured his hamstring. New York leads the American League East by 5 ½ games.

Aaron Judge is batting .391 with 21 home runs, 50 RBI, 86 hits, and an on-base percentage of .485 to lead New York in each of the five categories. Trent Grisham is second in home runs with 13. New York is batting .259 with a .468 slugging percentage. On Wednesday, New York will send Clarke Schmidt to the mound. The right-hander is 2-2 with a 3.95 ERA, 42 Ks, and 20 BBs.

New York wins at home on Wednesday, but the play here is UNDER. The UNDER has cashed in 12 of Cleveland's last 18 and 12 of New York's last 17. Cleveland starter Luis Ortiz has performed well over the last four outings, allowing seven runs on 11 hits across 22 innings. New York starter Clarke Schmidt is coming off a strong outing, allowing no runs on four hits across six innings. Final Score Prediction, New York Yankees win but our best play is UNDER 3-1.