Guardians vs Twins Picks and Prediction – 5/19/2025

The Cleveland Guardians open a three-game series on the road Monday versus the Minnesota Twins. Cleveland is 25-20 following its 4-1 loss to the Cincinnati Reds on Saturday. Cleveland has lost each of the first two games of its three-game series with Cincinnati that concludes on Sunday. The Guardians have lost three straight and trail first place in the American League Central by 4 ½ games. Keep up to date with all the MLB action with our MLB picks.

Steven Kwan is batting .318 to lead Cleveland and has team highs in hits with 56 and on-base percentage with .378. Kyle Manzardo is the leader in home runs with 10 and RBI with 25. Cleveland is batting .306 with a .381 slugging percentage. On Monday, the Cleveland Guardians will send Logan Allen to the mound. The left-hander is 2-2 with a 3.70 ERA, 31 Ks, and 20 BBs.

The Minnesota Twins improved to 26-20 following Saturday’s 7-0 victory over the Milwaukee Brewers. Pablo Lopez combined with three members of the bullpen to shut out the Brewers. Minnesota has posted three straight shutout victories, and the Twins have won 13 straight. Minnesota is second in the American League Central, four games behind the first-place Detroit Tigers.

Byron Buxton is batting .261 with 10 home runs and 27 RBI to lead Minnesota in the three categories. Ty France is the leader it hits with 42, and Trevor Larnach is the leader in on-base percentage with .323. Minnesota is batting .244 with a .387 slugging percentage. On Monday, Minnesota will send Bailey Ober to the mound. The right-hander is 4-1 with a 3.72 ERA, 40 Ks and 12 BBs.

Minnesota will win on Monday when hosting Cleveland, but the play here is UNDER. The UNDER has cashed in five of Cleveland's last six and 12 of Minnesota's last 17. Minnesota pitching has posted three consecutive shutouts through Saturday’s 7-0 win, and each of the three cashed UNDER. Minnesota starter Bailey Ober has had five consecutive solid outings, and on April 28, gave up just one run in 7.2 innings to beat Cleveland. Final Score Prediction, Minnesota Twins win but our best play is UNDER 4-1.