Guardians vs Angels Picks and Prediction – 4/5/2025

By: Kim Smith |

Last Updated: 04/03/2025 at 8:34 PM ET

Cleveland Guardians at Los Angeles Angels 04/04/25 - MLB Picks & Predictions
Game Start: 4/5/2025, 1:38 AM UTC
Latest Odds: CLE -120 ; O/U 7.5

Guardians vs Angels Prediction

The Cleveland Guardians are going to take on the Angels on the West Coast on Friday at 9:38 PM EST. The game is taking place at Angel Stadium and is being aired on CLEGuardians TV. Be ready for the baseball season with all of our MLB free picks.

Cleveland in their last 5 games have struggled immensely with a 1-4 record. The last game on the field for the Cleveland team was a 5-2 loss to the Padres. The Guardians are now sitting on a record of 2-4 on the year overall.

On the season the Guardians have ended up hitting at a clip of .227 with 7 homers and a total of 20 runs. The Guardians have ended up getting a .295 OBP and a .392 slugging percentage. The pitching staff for the Cleveland Guardians have ended up getting a 4.41 ERA and a 1.47 WHIP, but has struck out 32 batters while letting them hit at a clip of .276.

The Los Angeles Angels are coming to this game here sitting on a 4-1 record. The last game for the Angels ended up being a loss to the Saint Louis Cardinals by a score of 12-5. The Angels are sitting on an impressive 4-2 mark on the year.

Hitting for the Angels has managed to be horrible, but good at the same time with a .198 average and a total of only 4 homers, but 24 runs have crossed the plate. The Angels have ended up getting a .267 OBP with a .310 slugging. The pitching staff for the Angels has a 4.58 ERA and a 1.38 WHIP. Still, the Angels have allowed 24 walks with 46 strikeouts and the opponents have hit at a clip of only .249. 

Guardians vs Angels Pick Analysis

The Angels are playing great on the year so far and are facing a Guardians team that has struggled quite a bit this year. Granted, the Angels are not hitting that well they are producing runs. Look for that type of run production to continue in this game here for the Angels who are able to win the game rather easily as the Guardians continue to struggle on the day. Final Score Prediction, Los Angeles Angels win 5-1.

Our Free MLB Pick for Los Angeles Angels vs Cleveland Guardians

Los Angeles Angels +100