Guardians vs Astros Picks and Prediction – 7/8/2025

The Cleveland Indians open a three-game series on the road Monday versus the Houston Astros. Cleveland is 40-47 following its 1-0 loss to the Detroit Tigers on Saturday. Cleveland has lost each of its last nine games, and the Guardians have been shut out in three of the last six. Cleveland is 4th in the American League Central, 14 ½ games behind first-place Detroit. Keep up to date with all the MLB action with our MLB predictions.

Jose Ramirez is batting .300 with 14 home runs, 39 RBI, and an on-base percentage of .362 to lead Cleveland in each of the four categories. Stephen Kwan leads in hits with 96. Cleveland is batting .224 with a .362 slugging percentage. On Monday, the Cleveland Guardians will send Tanner Bibee to the mound. The right-hander is 4-2 with a 4.20 ERA, 87 Ks, and 30 BBs.

The Houston Astros improved to 54-35 following Saturday’s 6-4 victory over the Los Angeles Dodgers. Yainer Diaz hit a home run, and Josh Hader recorded the last four outs for his 25th save, which leads the majors. Houston has won two straight and five of the last six. The Astros lead the American League West by seven games over the Seattle Mariners. 

Jeremy Pena is batting .322 with 102 hits and an on-base percentage of .378 to lead Houston in each of the three categories. Isaac Paredes leads Houston in home runs with 18 and RBI with 48. Houston is batting .261 with a .410 slugging percentage. On Monday, Houston will send Hunter Brown to the mound. The right-hander is 9-3 with a 1.82 ERA, 126 Ks, and 29 BBs.

Houston will win at home on Monday when hosting the Cleveland Guardians, but the play here is UNDER. The UNDER has cashed in five of Cleveland's last six. These two played a three-game series in early June, and two of the three games cashed UNDER. Houston starter Hunter Brown has performed well in each of the last five outings, allowing six runs on 18 hits across 30.1 innings, with the UNDER cashing in four of the five. Final Score Prediction: Houston Astros win but our best play is UNDER 4-1.