Guardians vs Tigers Picks and Prediction – 5/22/2025

The Cleveland Guardians will be on the road Thursday for game one of four in Detroit against the Tigers. Cleveland has found success this season coming into this matchup with 25 wins overall riding a long losing streak following the one run loss to Minnesota last time out. Offensively Cleveland has been lackluster with a .233 batting average the guardians have scored 182 runs on 346 hits. The Cleveland pitching has been equally as bad with a 4.14 ERA as the Guardians have allowed 27 runs over their last five losses. Stay up to date with our MLB Picks.

Steven Kwan leads the Cleveland offense this season with a .311 batting average and 56 hits overall. Jose Ramirez has a .295 batting average and Angel Martinez has a .292 batting average. Kyle Manzardo leads Cleveland this season with 10 home runs and 26 RBI's on the year.

The Detroit Tigers return home Thursday with 33 wins on the year having won four of the last six overall including two in a row following their victory against Saint Louis on Wednesday. Offensively Detroit hits the ball well with a .259 batting average the tigers have scored 262 runs on 433 hits. The Detroit pitching has been phenomenal this season with a 3.37 team ERA.

Zach McKinstry leads the Detroit offense this season with a .289 batting average. Riley Greene is one of two players with a team high twelve home runs this season and leads Detroit with 53 hits. Spencer Torkelson has a .240 batting average to go along with the team leading 38 RBIs this season for Detroit. Manuel Margot has a .316 batting average for Detroit but has played just six times this season.

Both teams have seen quite a bit of success this year as each come into this game with winning records. Look for Detroit to to the work however as they are the better overall team. The Tigers have the stronger offense and better pitcher on the mound. Take Detroit Thursday night to do the work against Cleveland. Final Score Prediction, Detroit Tigers win 6-3.