Guardians vs White Sox Picks and Prediction – 7/12/2025

The Cleveland Guardians play the third game of a four-game series on the road Saturday versus the Chicago White Sox. Cleveland is 43-48 following Wednesday’s 4-2 win over the Houston Astros. Cleveland swept Houston in its three-game series. Cleveland’s game on Thursday versus Chicago was postponed due to rain. Cleveland is 4th in the American League Central, 14 ½ games behind first-place Detroit. Keep up to date with all the MLB action with our expert MLB picks.

Jose Ramirez is batting .301 with 17 home runs, 45 RBI, and an on-base percentage of .366 to lead Cleveland in each of the four categories. Steven Kwan leads in hits with 101. Cleveland is batting .224 with a .366 slugging percentage. On Saturday, Cleveland will send Tanner Bibee to the mound. The right-hander is 4-9 with a 4.35 ERA, 90 Ks, and 31 BBs.

The Chicago White Sox are 31-62 following a 2-1 victory on Wednesday over the Toronto Blue Jays. Chicago starter Adrian Houser gave up just one run on seven hits in seven innings to help lead the White Sox to the victory. Chicago snapped a three-game losing streak with the win. The White Sox are last in the American League Central, 27 ½ games behind first-place Detroit.

Lenya Sosa is batting .272 to lead Chicago and has a team high of 74 hits. Andrew Benintendi leads in home runs with 10 and RBI with 34, while Miguel Vargas leads in on-base percentage at .301. Chicago is batting .222 with a .345 slugging percentage. On Saturday, Chicago will send Sean Burke to the mound. The right-hander is 4-8 with a 4.40 ERA, 75 Ks, and 41 BBs.

Although the UNDER has cashed much more often than not for these two teams of late, the play here is OVER. Both starting pitchers have struggled on the mound of late, and that will carry over into Saturday’s game. Cleveland starter Tanner Bibee has been hit hard in each of the last two outings, allowing nine runs on 10 hits across 8.2 innings. Chicago starter Sean Burke was hit hard last time out, allowing six runs on six hits across five innings. Final Score Prediction: Chicago White Sox win but our best play is OVER 7-6.