Guardians vs Cubs Picks and Prediction – 7/4/2025

By: Cameron Ross |

Last Updated: 07/02/2025 at 9:49 PM ET

Cleveland Guardians at Chicago Cubs 07/03/25 - MLB Picks & Predictions
Game Start: 7/4/2025, 12:05 AM UTC
Latest Odds: CHC -161 ; O/U 8.5

Guardians vs Cubs Prediction

The Cleveland Guardians stay on the road Thursday night with another game in Chicago against the Cubs. Cleveland has forty wins and 43 losses on the year coming into Thursday riding a long losing streak following a three run loss in Game 1 of this series. Offensively, Cleveland has struggled all season with a .225 team batting average. The Guardians have scored just 305 runs on 608, that's. The Cleveland pitching has been horrendous as well with the 4.05 team ERA. Stay up to date with our MLB Picks.

Jose Ramirez leads the Cleveland offense this season with a .305 batting average, thirteen home runs, and 38 RBI's. Carlos Santana has a .236 batting average and Gabriel Arias has a .231 batting average. Kyle Manzardo has a .237 batting average and is also tied for the team lead with 13 home runs this season.

The Chicago Cubs stay home Thursday night with fifty wins and 35 losses on the year having won three of the last five overall. Offensively Chicago has a .257 batting average as they have scored 458 runs on 755 hits this season. The Chicago pitching has been top tier with a 3.84 team ERA this season.

Nico Hoerner leads the Chicago offense this season with a .290 batting average. Kyle Tucker has a .290 batting average as well to go along with the team leading 92 hits. Dansby Swanson has a .245 batting average and Ian Happ has a .237 batting average. Seiya Suzuki leads Chicago with 23 home runs and 70 RBIs through 81 games played. Miguel Amaya has a .280 batting average for Chicago this season but has played in just 27 games. Michael Busch has been solid for the Chicago offense this season with a .282 batting average and fifty RBIs.

Guardians vs Cubs Pick Analysis

The Cubs are the better team in this game and it will again show Thursday. Look for Chicago to control this game start to finish leading to the win. The Cubs will overpower Cleveland Thursday resulting in the win at home. Final Score Prediction, Chicago Cubs win 7-3.

Our Free MLB Pick for Chicago Cubs vs Cleveland Guardians

Chicago Cubs -161