Reds vs Cardinals Picks and Prediction – 6/20/2025

The Cincinnati Reds open a three-game series Friday versus the St Louis Cardinals. Cincinnati improved to 39-35 following Wednesday’s 4-2 victory over the Minnesota Twins. Spencer Steer hit a two-run home run for the Reds, and Nick Lodolo gave up just two runs in five innings. The Reds have won four straight and trail first-place Chicago by 6 ½ games in the National League Central. Keep up to date with all the MLB action with our MLB previews.

TJ Friedl is batting .288 with 77 hits and an on-base percentage of .381 to lead Cincinnati in the three categories. Elly De La Cruz leads the Reds in home runs with 16 and in RBI with 50. Cincinnati is batting .248 with a .404 slugging percentage. On Friday, the Cincinnati Reds will send Brady Singer to the mound. The right-hander is 7-4 with a 4.34 ERA, 60 Ks, and 32 BBs.

The St Louis Cardinals improved to 38-35 following Tuesday’s 12-2 victory over the Chicago White Sox. Brendan Donovan had four hits, while Ivan Herrera knocked in four runs for the Cardinals. St. Louis’ game schedule for Wednesday versus Chicago was rained out. St Louis trails first-place Chicago by seven games in the National League Central.

Brendan Donovan is batting .323 with 83 hits and an on-base percentage of .388 to lead St Louis in the three categories. Willson Contreras leads in home runs with nine and RBI with 45. St Louis is batting .257 with a .393 slugging percentage. On Friday, the St Louis Cardinals will send Sonny Gray to the mound. The right-hander is 7-2 with a 3.84 ERA, 85 Ks, and 15 BBs.

The Cincinnati Reds have won nine of the last 11, while St Louis has lost seven of its last eight. Cincinnati starter Brady Singer has had two consecutive solid outings, allowing three runs on nine hits across 11 innings. St Louis starter Sonny Gray is coming off a poor outing, in which the right-hander allowed six runs on eight hits across 4.1 innings. Final Score Prediction: Cincinnati Reds win 6-2.