Reds vs Giants Picks and Prediction – 4/8/2025

By: Thomas Pemberton |

Last Updated: 04/06/2025 at 9:36 PM ET

Cincinnati Reds at San Francisco Giants 04/07/25 - MLB Picks & Predictions
Game Start: 4/8/2025, 1:45 AM UTC
Latest Odds: SFG -145 ; O/U 7

Reds vs Giants Prediction

The Cincinnati Reds head to San Francisco on Monday to take on the Giants in a three game series. The Reds are 3-7 on the season. Cincinnati lost to the Brewers 8-2 on Sunday. The Reds are averaging 4.1 runs scored per game with 7 hits. Cincinnati carries a .215 batting average. Stay up to date with our expert's MLB Picks. 

Hunter Greene will make his 3rd start on the mound for the Cincinnati Reds. Greene is 0-1 on the season with 12 innings pitched. Greene has 16 strikeouts and carries a 2.25 ERA. The Cincinnati Reds carry a 2.85 team ERA. 

The San Francisco Giants are 8-1 on the season. The Giants have won eight of their last ten games. San Francisco is riding a seven game win streak and they carry a 2-0 home field record. The Giants are averaging 5.5 runs scored per game with 8.4 hits. 

Logan Webb will make his 3rd start on the mound for the San Francisco Giants. Webb is 1-0 on the season with 12 innings pitched. Webb has 11 strikeouts and carries a 3.00 ERA. The San Francisco Giants carry a 2.71 team ERA.

Reds vs Giants Pick Analysis

The San Francisco Giants have the momentum heading into this series. The Giants are seeking a ninth straight win. The Cincinnati Reds have allowed 15 runs over their last two games. The Giants show the best value as home favorites. Final Score Prediction, San Francisco Giants win 7-4. 

Our Free MLB Pick for San Francisco Giants vs Cincinnati Reds

San Francisco Giants -145