Reds vs Brewers Picks and Prediction – 4/6/2025

The Cincinnati Reds (2-6) are set to face the Milwaukee Brewers (4-4) at American Family Field on Sunday, April 6, 2025, with the first pitch scheduled for 2:10 PM ET. Both teams are looking to gain momentum early in the season.​ Get in on the action with our free MLB picks.

The Reds have had a challenging start to their 2025 campaign, currently holding a 2-6 record. Offensively, the team has struggled, averaging 3.4 runs per game with a collective batting average of .197. They have recorded 24 runs batted in and seven home runs over their first eight games. On the mound, the Reds have been more effective, posting a team ERA of 2.47, which ranks fifth in MLB. Their pitching staff has allowed 20 total runs and seven home runs, with a WHIP of 0.85. ​

Right-hander Carson Spiers is slated to make his second start of the season. In his debut, Spiers delivered an impressive performance, throwing six scoreless innings and allowing only three hits. ​

The Brewers enter the game with a 4-4 record, aiming to build consistency. Offensively, Milwaukee has shown promise, with second baseman Brice Turang leading the charge. Turang is currently on a nine-game hitting streak to start the season, and is the diamond of this offense.

On the mound, right-hander Chad Patrick is expected to start for the Brewers. Patrick has made one appearance this season, recording a 3.18 ERA over 5.2 innings pitched, with six strikeouts and four walks.

This early-season matchup provides both teams an opportunity to establish momentum. Both Cincinnati and Milwaukee have struggled to get out of the gate, but Cincinnati has the offensive talent and momentum over the last two games to gut out a big road win here. We like the Reds to win this one 4-2.