Reds vs Marlins Picks and Prediction – 4/21/2025

In Monday night MLB action, the Cincinnati Reds will travel to loanDepot Park to take on the Miami Marlins. Be ready for the baseball season with all of our MLB predictions. The Reds (11-11) have split their first ten road games and are two games back in the NL Central Division race. On Sunday, 3B Noelvi Marte and C Austin Wynns went a combined 11-for-14 with 13 RBIs to power Cincinnati to a 24-2 road triumph against Baltimore. 

Twenty-seven year old southpaw Nick Lodolo (2-1 2.31 ERA) has gotten off to a nice start to the year for the Reds. Through 23 plus innings, Lodolo has issued just two walks and owns a minuscule 0.81 WHIP.

The Miami Marlins are a game below .500 at home and are tied with Washington for third place in the NL East Division standings. On Sunday, OF Javier Sanoja homered and drove in five runs to lead Miami to a 7-5 road victory against Philadelphia in ten innings. 3B Connor Norby added three hits and scored twice for the Marlins (9-12), who snapped a five-game losing streak.

Twenty-six year old righty Max Meyer (1-2 2.63 ERA) will make his 18th career major league start for the Marlins. Last time out, Meyer (6 IP) gave up three runs and fanned eight batters during a 6-2 home loss versus Arizona. 

Miami OF Griffin Conine has been placed on the 60-day injured list with a dislocated left shoulder. Through 22 games, Cincinnati ranks 22nd in OPS and 15th in runs scored. For the regular season, Miami ranks 14th in OPS and 18th in runs scored. Take the Reds to win on the road. Final Score Prediction, Cincinnati Reds win 5-3.