Reds vs Royals Picks and Prediction – 5/26/2025

By: David Anicetti |

Last Updated: 05/25/2025 at 9:02 PM ET

Cincinnati Reds at Kansas City Royals 05/26/25 - MLB Picks & Predictions
Game Start: 5/26/2025, 8:10 PM UTC
Latest Odds: KAN -120 ; O/U 8

Reds vs Royals Prediction

The Cincinnati Reds open a three-game series on the road Monday versus the Kansas City Royals. Cincinnati is 26-27 following its 6-4 victory over the Chicago Cubs on Saturday. Elly De La Cruz hit a home run and had four RBI to help lead Cincinnati to the victory. Cincinnati snapped a three-game losing streak with the win. Cincinnati trails first-place Chicago in the National League Central by 5 ½ games. Keep up to date with all the MLB action with our MLB predictions.

Gavin Lux is batting .293 to lead Cincinnati and has a team-high .383 on-base percentage. Elly De La Cruz is the leader in home runs with nine and in RBI with 37. TJ Friedl is the leader in hits with 53. Cincinnati is batting .244 with a .394 slugging percentage. On Monday, Cincinnati will send Nick Martinez to the mound. The right-hander is 2-5 with a 3.43 ERA, 43 Ks, and 13 BBs.

The Kansas City Royals dropped to 28-25 following Saturday’s 5-4 loss to the Minnesota Twins. Kansas City lost its second straight game in walk-off fashion when the Twins scored in the bottom of the 9th inning. The Royals have lost two straight and three of the last four. Kansas City is fourth in the American League Central, five games behind the first-place Detroit Tigers.

Maikel Garcia is batting .312 with a .375 on-base percentage to lead Kansas City in both categories. Vinnie Pasquantino is the leader in home runs with eight and RBI with 30. Bobby Witt Jr is the leader in hits with 62. Kansas City has a .246 batting average with a .363 slugging percentage. On Monday, Kansas City will send Michael Lorenzen to the mound. The right-hander is 3-5 with a 3.77 ERA, 50 Ks, and 16 BBs.

Reds vs Royals Pick Analysis

Cincinnati has won six of its last nine, while Kansas City has lost seven of its last 10. Cincinnati starter Nick Martinez has had two consecutive strong outings, allowing one run on six hits across 13 innings. Kansas City starter Michael Lorenzo has been hit hard in two consecutive outings, allowing six runs on 14 hits across 12 innings. Final Score Prediction: Cincinnati Reds win 5-2.

Our Free MLB Pick for Kansas City Royals vs Cincinnati Reds

Cincinnati Reds +100