Reds vs Orioles Picks and Prediction – 4/19/2025

By: David Anicetti |

Last Updated: 04/18/2025 at 6:43 PM ET

Cincinnati Reds at Baltimore Orioles 04/19/25 - MLB Picks & Predictions
Game Start: 4/19/2025, 8:05 PM UTC
Latest Odds: CIN -128 ; O/U 8.5

Reds vs Orioles Prediction

The Cincinnati Reds play the second game of a three-game series on the road Saturday versus the Baltimore Orioles. Cincinnati is 9-10 following its 11-7 loss to the Seattle Mariners on Thursday. Cincinnati has won four of the last six but is two games behind the first-place Chicago Cubs in the National League East. Keep up to date with all the MLB action with our MLB picks.

Gavin Lux is batting .290 to lead Cincinnati and has a team-high .371 on-base percentage. Matt McLain is the leader in home runs with three, and Elly De La Cruz is the leader in RBI with 18. TJ Friedl is the hits leader with 19. Cincinnati is batting .213 with a .337 slugging percentage. On Saturday, Cincinnati will send Hunter Greene to the mound. The right-hander is 2-1 with a 0.98 ERA, 31 Ks, and 4 BBs.

The Baltimore Orioles improved to 8-10 following a 6-2 victory over the Cleveland Guardians on Thursday. The Orioles won the final two games of their series with the Guardians, but are just 3-4 over the last seven. Baltimore is fourth in the American League East, trailing the first-place New York Yankees 3 ½ games.

Cedric Mullins is batting .291 with four home runs, 17 RBI, 16 hits, and an on-base percentage of .443 to lead Baltimore in the five categories. Adley Rutschman and Jordan Westburg each have three home runs for the Orioles. Baltimore is batting .234 with a slugging percentage of .403. The Orioles have not yet announced a starting pitcher for Saturday's second game of a three-game series at home versus Cincinnati.

Reds vs Orioles Pick Analysis

Cincinnati and Baltimore have struggled to start the regular season, but Cincinnati will have its ace on the mound on Saturday. The Reds have won six of the last nine. Baltimore has lost four of the last six versus an opponent from the National League. Cincinnati starter Hunter Greene has had four consecutive strong outings, allowing three runs across 27.2 innings. Final Score Prediction: Cincinnati Reds win 5-2.

Our Free MLB Pick for Baltimore Orioles vs Cincinnati Reds

Cincinnati Reds -128