White Sox vs Rays Picks and Prediction – 7/22/2025

The Chicago White Sox play the second game of a three-game series on the road Tuesday versus the Tampa Bay Rays. Chicago is 35-65 following Sunday’s 7-2 victory over the Pittsburgh Pirates. Chicago swept Pittsburgh in a three-game series, and the White Sox have won four of the last six. Chicago trails first-place Detroit in the American League Central by 25 games. Keep up to date with all the MLB action with our expert MLB picks.

Lenya Sosa is batting .270 with 81 hits to lead Chicago in both categories. Andrew Benintendi leads Chicago in home runs with 11, while Luis Robert Jr leads in RBI with 38, and Miguel Vargas is the leader in on-base percentage at .326. Chicago has not announced its starting pitcher for Tuesday’s matchup on the road against the Tampa Bay Rays. 

The Tampa Bay Rays dropped to 52-48 following Sunday’s 5-3 loss to the Baltimore Orioles. Tampa Bay had its two-game winning streak snapped by Sunday’s loss. The Rays have lost five of the last seven with only a pair of victories over Baltimore during that span. The Rays trail first-place Toronto in the American League East by 6 ½ games.

Jonathan Aranda is batting .316 with an on-base percentage of .392 to lead Tampa Bay in both categories. Junior Caminero leads in home runs with 25 and RBI with 65, while Yandy Diaz leads in hits with 111. Tampa Bay is batting .258 with a .406 slugging percentage. On Tuesday, Tampa Bay will send Drew Rasmussen to the mound. The right-hander is 7-5 with a 2.86 ERA, 77 Ks, and 22 BBs.

The Chicago White Sox will pick up a victory on the road Tuesday when visiting the Tampa Bay Rays. Chicago has won five of its last six on the road, and the White Sox have won four of the last six overall. Tampa Bay has lost five of its last seven. Tampa Bay’s Drew Rasmussen has allowed just two runs on six hits in the last two starts, but pitched just four innings across the two games. Final Score Prediction: Chicago White Sox win 5-3.