White Sox vs Athletics Picks and Prediction – 4/27/2025

By: David Anicetti |

Last Updated: 04/26/2025 at 9:23 PM ET

Chicago White Sox at Sacramento Athletics 04/27/25 - MLB Picks & Predictions
Game Start: 4/27/2025, 8:05 PM UTC
Latest Odds: ATH -220 ; O/U 9.5

White Sox vs Athletics Prediction

The Chicago White Sox complete a three-game series on the road Sunday versus the Athletics. Chicago is 6-20 following its 6-5 loss to the Athletics on Friday in the opening game of the series. Chicago has lost four of the last five, with only a victory over Minnesota during that span. The White Sox are last in the American League Central, 9 ½ games behind first-place Detroit. Keep up to date with all the MLB action with our expert MLB picks.

Lenyn Sosa is batting .276 with 24 hits and a .300 on-base percentage to lead Chicago in the three categories. Andrew Benintendi is the leader in home runs with four, and Brooks Baldwin is the leader in RBI with 12. Chicago is batting .205 with a .316 slugging percentage. On Sunday, Chicago will send Davis Martin to the mound. The right-hander is 1-3 with a 3.95 ERA, 16 Ks, and 9 BBs. 

The Athletics improved to 13-13 following Friday’s one-run victory over Chicago. Jacob Wilson had a home run and three RBI while Brent Rooker hit an RBI double to put the Athletics ahead in the 7th and four of the last six. The Athletics are fourth in the American League West, trailing the first-place Texas Rangers by two games and are just one game behind second-place Seattle.  

Jacob Wilson is batting .347 to lead the Athletics and has a team-high 34 hits. Tyler Soderstrom is the leader in home runs with nine, RBI with 22, and on-base percentage at .369. The Athletics are batting .256 with a .433 slugging percentage. On Sunday, the Athletics will send Osvaldo Bido to the mound. The right-hander is 2-2 with a 4.85 ERA, 16 Ks, and 10 BBs. 

White Sox vs Athletics Pick Analysis

Chicago will pick up a victory in the final game of this series with the Athletics behind a strong performance on the mound from its starting pitcher. Chicago starter Davis Martin is coming off a strong outing in which the right-hander allowed no runs on three hits across five innings. Athletics starter Osvaldo Bido is coming off a poor outing in which the right-hander allowed eight runs on eight hits across 5.1 innings. Final Score Prediction: Chicago White Sox win 6-3.

Our Free MLB Pick for Sacramento Athletics vs Chicago White Sox

Chicago White Sox +200