White Sox vs Athletics Picks and Prediction – 4/26/2025

The Chicago White Sox play the second game of a three-game series on the road Saturday versus the Athletics. Chicago is 6-19 following a 3-0 victory over the Minnesota Twins on Thursday in a game that was shortened to seven innings due to rain. Chicago snapped a three-game losing streak with the win, but trails first place in the American League Central by nine games. Keep up to date with all the MLB action with our MLB predictions.

Lenyn Sosa is batting .265 with 22 hits and an on-base percentage of .291 to lead Chicago in the three categories. Andrew Benintendi is the leader in home runs with four, and Andrew Vaughn is the leader in RBI with 10. Chicago is batting .203 with a .319 slugging percentage. On Saturday, Chicago will send Jonathan Cannon to the mound. The right-hander is 0-3 with a 4.81 ERA, 22 Ks, and 15 BBs.

The Athletics improved to 12-13 following a 4-3 victory over the Texas Rangers on Thursday. Jacob Wilson hit a two-out single in the 9th inning to drive in the winning run for the Athletics. The Athletics won two of three in their series with the Rangers. The Athletics are last in the American League West, two games behind co-leaders the Seattle Mariners and Texas Rangers.

Jacob Wilson is batting .330 with 31 hits to lead the Athletics in both categories. Tyler Soderstrom leads in home runs with nine and RBI with 21. Lawrence Butler is the leader in on-base percentage at .358. The Athletics are batting .254 with a .432 slugging percentage. On Saturday, the Athletics will send Jeffrey Springs to the mound. The left-hander is 3-2 with a 5.64 ERA, 23 Ks, and 14 BBs.

Chicago has struggled early this season, but will have a pitcher on the mound who performed well versus the Athletics earlier this month. Chicago starter Jonathan Cannon pitched well on April 16 versus the Athletics, allowing no runs on three hits across 4.1 innings. Athletics starter Jeffrey Springs has been hit hard in four consecutive outings, allowing 14 runs across 16.1 innings. Final Score Prediction: Chicago White Sox wins 5-2.