White Sox vs Pirates Picks and Prediction – 7/19/2025

The Chicago White Sox play the second game of a three-game series on the road Saturday versus the Pittsburgh Pirates. Chicago is 32-65 and lost to the Cleveland Guardians 6-5 last Sunday in the final game before the All-Star Game break. Chicago has lost six of the last eight and trails the first-place Detroit Tigers in the American League Central by 27 games. Keep up to date with all the MLB action with our expert MLB picks.

Lenya Sosa is batting .290 to lead Chicago and has a team high of 77 hits. Andrew Benintendi leads Chicago in home runs with 11 and RBI with 35, while Miguel Vargas leads in on-base percentage at .297. Chicago is batting .220 with a .344 slugging percentage. On Saturday, Chicago will send Adrian Houser to the mound. The right-hander is 5-2 with a 1.56 ERA, 39 Ks, and 18 BBs.

The Pittsburgh Pirates are 39-58 following Sunday’s 2-1 victory over the Minnesota Twins that avoided a sweep after Pittsburgh lost the first two games of that series. Pittsburgh snapped an eight-game losing streak with Sunday’s win before the All-Star Game break. The Pirates are last in the National League Central, 18 ½ games behind the first-place Chicago Cubs.

Andrew McCutchen is batting .255 with an on-base percentage of .335 to lead Pittsburgh in both categories. Oneil Cruz leads Pittsburgh in home runs with 16, while Bryan Reynolds leads in RBI with 46 and hits with 80. Pittsburgh is batting .230 with a .339 slugging percentage. On Saturday, Pittsburgh will send Mike Burrows to the mound. The right-hander is 1-3 with a 4.83 ERA, 42 Ks, and 17 BBs.

While the UNDER is a solid choice, the play here is the Chicago White Sox. Pittsburgh has lost eight of its last nine games and arrives struggling at the plate. Chicago's Adrian Houser has had four consecutive strong outings, allowing three runs on 22 hits across 28.1 innings. Pittsburgh’s Mike Burrows was hit hard last time out, allowing six runs on five hits across 1.1 innings. Final Score Prediction: Chicago White Sox win 4-2.