White Sox vs Mets Picks and Prediction – 5/27/2025

By: David Anicetti |

Last Updated: 05/26/2025 at 9:17 PM ET

Chicago White Sox at New York Mets 05/27/25 - MLB Picks & Predictions
Game Start: 5/27/2025, 11:10 PM UTC
Latest Odds: NYM -275 ; O/U 8

White Sox vs Mets Prediction

The Chicago White Sox play the second game of a three-game series on the road Tuesday versus the New York Mets. Chicago dropped to 17-36 following its 5-4 loss to the Texas Rangers on Sunday. Nevertheless, Chicago has won two of the last three, but trails first place in the American League Central by 16 ½ games. Keep up to date with all the MLB action with our expert MLB picks.

Lenyn Sosa is batting .283 with 49 hits to lead Chicago in both categories. Miguel Vargas is the leader in home runs with seven, RBI with 23, and on-base percentage at .316. Chicago is batting .221 with a .343 slugging percentage. On Tuesday, the Chicago White Sox will send Shane Smith to the mound. The right-hander is 1-3 with a 2.36 ERA, 49 Ks, and 18 BBs.

The New York Mets improved to 32-21 following Sunday’s 3-1 victory over the Los Angeles Dodgers. Pete Alonso ended the longest home run drought of his MLB career with a two-run homer to help lead the Mets to the win. New York has won three of the last four but trails the first-place Philadelphia Phillies in the National League East by two games.

Pete Alonso is batting .291 with 40 RBI and a .391 on-base percentage to lead New York in the three categories. Francisco Lindor is the leader in home runs with 10 and hits with 57. New York is batting .245 with a .404 slugging percentage. On Tuesday, the New York Mets will send Tylor Megill to the mound. The right-hander is 3-4 with a 3.56 ERA, 66 Ks, and 23 BBs.

White Sox vs Mets Pick Analysis

Although the UNDER has cashed more often than not of late for these two, the play here is OVER. Both starting pitchers have struggled of late, and hitters will take advantage of that early and often. Chicago starter Shane Smith struggled last time out, allowing three runs on two hits. New York starter Tylor Megill has allowed 16 runs across the last 23.1 innings, with the OVER cashing in four of five during that span. Final Score Prediction: New York Mets win but our best play is OVER 8-4.

Our Free MLB Pick for New York Mets vs Chicago White Sox

Over 8