White Sox vs Twins Picks and Prediction – 4/24/2025

The Thursday MLB schedule will get underway with a matinee between the Chicago White Sox and the Minnesota Twins from Target Field. Be ready for the baseball season with all of our MLB predictions. The White Sox (5-19) have dropped 11 of their first 12 road games and own the worst overall record in the American League. Last night, Chicago batters went 1-for-8 with runners in scoring position and left seven men on base during a 6-3 road loss against Minnesota. 

Twenty-five year old righty Shane Smith (0-1 2.82 ERA) will make his fifth start of the year for the White Sox. Through 22 plus innings, Smith has struck out 15 batters and owns a sparkling 0.94 WHIP.

The Minnesota Twins are a game above .500 at home and are sitting in fourth place in the AL Central Division standings. On Wednesday, Minnesota OF Trevor Lamach broke a sixth inning tie with a solo shot and OF Byron Buxton sealed the victory with a two-run blast. DH Edouard Julien went 2-for-4 and scored a run out of the leadoff spot for the Twins, who improved to 9-15 overall.

Minnesota manager Rocco Baldelli will turn to struggling right-hander Chris Paddack (0-2 7.27 ERA) in the series finale. Control has been an issue for Paddack, who has allowed nine walks and four long balls across 17 plus frames. 

Minnesota 3B Royce Lewis (hamstring) is expected to begin a rehab assignment this week and should return to the lineup early next month. Through 24 games, Chicago ranks 30th in OPS and 28th in runs scored. For the regular season, Minnesota ranks 28th in OPS and 26th in runs scored. Take the under. Final Score Prediction, Minnesota Twins win 4-2.