White Sox vs Royals Picks and Prediction – 5/6/2025

The Chicago White Sox play the second game of a four-game series on the road Tuesday versus the Kansas City Royals. Chicago improved to 10-24 following its 5-4 victory over the Houston Astros on Sunday. Chicago has won three of the last four. The White Sox are last in the American League Central, 11 ½ games behind first place. Keep up to date with all the MLB action with our expert MLB picks.

Lenya Sosa is batting .256 to lead Chicago and has a team-best 30 hits. Andrew Benintendi is the leader in home runs with five, and Luis Robert Jr is the leader in RBI with 15 and on-base percentage at .313. Chicago is batting .216 with a .328 slugging percentage. On Tuesday, Chicago will send Sean Burke to the mound. The right-hander is 2-4 with a 4.91 ERA, 25 Ks, and 14 BBs.

The Kansas City Royals improved to 19-16 following Sunday’s 11-6 victory over the Baltimore Orioles. Maikel Garcia hit a pair of home runs for Kansas City as the Royals set a new franchise record of seven home runs in one game. The Royals have won two straight and five of the last six. The Royals are third in the American League Central, three games behind first place. 

Maikel Garcia is batting .319 to lead Kansas City. Vinnie Pasquantino is the leader in home runs with six and RBI with 22. Bobby Witt Jr is the leader in hits with 41 and on-base percentage at .379. Kansas City is batting .237 with a .360 slugging percentage. On Tuesday, Kansas City will send Seth Lugo to the mound. The right-hander is 3-3 with a 3.07 ERA, 34 Ks, and 12 BBs.

The Kansas City Royals will win at home on Tuesday despite facing a tough starting pitcher. Chicago starter Sean Burke is coming off a strong outing in which the right-hander allowed no runs on two hits across six innings. However, KC has won 11 of the last 13 while Chicago is just 6-14 in the last 20. Kansas City starter Seth Lugo has had two consecutive strong outings, allowing two runs across 14 innings. Final Score Prediction: Kansas City Royals win 6-3.