White Sox vs Tigers Picks and Prediction – 4/4/2025

The Chicago White Sox open a three-game series on the road Friday in Motown versus the Detroit Tigers. Chicago is 2-4 following a 6-1 loss to the Minnesota Twins on Wednesday. Chicago lost two out of three to Minnesota, winning the first of the three-game set, before losing each of the last two. Chicago is tied with each of the other four clubs in the American League Central at 2-4. Keep up to date with all the MLB action with our expert MLB picks.

Andres Benintendi is batting .333 with two home runs, six RBI, seven hits, and an on-base percentage of .391 to lead Chicago in each of the five categories. Chicago has a team batting average of .214 and a slugging percentage of .380. On Friday, the Chicago White Sox will send Jonathan Cannon to the mound. The right-hander is 0-0 with a 0.00 ERA, 5 Ks, and 3 BBs.

The Detroit Tigers look to bounce back from a loss with a victory on Friday when they open their series at home with the White Sox. Detroit is 2-4 and as mentioned previously, tied with each of the other four clubs in the AL Central with identical records. Detroit lost to the Seattle Mariners 3-2 on Wednesday but won each of the first two games of its series versus the Mariners

Spencer Torkelson is batting .318 with an on-base percentage of .444 to lead Detroit in both categories. Riley Greene is the leader in home runs with two and hits with eight. Dillon Dingler is the leader in RBI with five. Detroit has a team batting average of .265 and a slugging percentage of .419. On Friday, Detroit will send Jack Flaherty to the mound. The right-hander is 0-0 with a 3.18 ERA, 5 Ks, and 2 BBs.

Detroit will pick up a win at home on Friday, but the play here is UNDER. The UNDER has cashed in six of Chicago's last 8 on the road, in 13 of the last 20 head-to-head between these two, and nine of Detroit's last 12 at home. Chicago starter Jonathan Cannon pitched well in his only outing, allowing four hits and no runs across five innings. Detroit starter Jack Flaherty gave up two runs on three hits across 5.2 innings last Friday. Final Score Prediction, Detroit Tigers win but our best play is UNDER 4-2.