White Sox vs Rockies Picks and Prediction – 7/5/2025

The 28-58 Chicago White Sox take on the 29-67 Colorado Rockies at Coors Field on July 4, first pitch set for 6:10 PM ET. Chicago will send Adrian Houser to the mound with a 1.90 ERA, while Colorado counters with struggling righty Antonio Senzatela, who comes in at 3-11 with a 6.69 ERA. Chicago dropped the last game to the Dodgers 5-4, while Colorado lost to Houston 5-3. Elevate your MLB game with our top-notch MLB picks.

The White Sox are 2-3 in the last five, but three of those games were decided by just one or two runs. They’ve been in more close games lately and found some offense, including a 5-2 win over the Giants last weekend. Houser gives them a legit shot, pitching to a 1.90 ERA and 1.17 WHIP over 42.2 innings, giving up just 2 home runs in that span. Offensively, Andrew Benintendi leads the team with 10 homers, but overall production has been inconsistent.

On the mound, Chicago holds a 4.14 ERA and 1.40 WHIP, which is average but far better than Colorado's. They’ve limited opponents to a .254 average. Injuries still linger with Davis Martin, Fraser Ellard, and Jared Shuster all on the IL, but none are top contributors right now. This is a team that doesn’t hit much (.221 batting average) this season.

Colorado has been brutal all season and enters this one at 8-34 at home. They've lost four of the last five, including back-to-back one-run losses to Houston. Hunter Goodman has been one of the few bright spots, hitting .286 with 16 home runs and 50 RBIs, but the rest of the lineup hasn’t done much to back him up. 

On the mound, the Rockies starters own a 5.50 ERA and 1.56 WHIP, and opponents are hitting .292 against them. Senzatela’s 6.69 ERA is glaring, and he’s surrendered 13 home runs and 125 hits in just 80.2 innings. Injuries continue to pile up with Kris Bryant, Ezequiel Tovar, and Ryan Feltner all out. The team’s .229 batting average is slightly better than Chicago’s, but it hardly matters when the pitching is this poor.

Chicago has the clear edge on the mound with Houser holding opponents to a .228 average while Senzatela has been batting practice all season. Colorado can’t stop anyone, giving up nearly six runs per game with the worst home record in baseball. Even with Chicago’s weak offense, Houser’s form and Colorado’s poor pitching staff make this a solid pick. Final Score Prediction: Chicago White Sox win 6-3.