White Sox vs Guardians Picks and Prediction – 4/9/2025

By: Cameron Ross |

Last Updated: 04/08/2025 at 9:34 PM ET

Chicago White Sox at Cleveland Guardians 04/09/25 - MLB Picks & Predictions
Game Start: 4/9/2025, 10:10 PM UTC
Latest Odds: CLE -194 ; O/U 7.5

White Sox vs Guardians Prediction

The Chicago White Sox stay on the road Wednesday with another game in Cleveland against the Cleveland Guardians. Chicago is one of the worst teams in baseball with just two wins through 10 games played riding a lengthy losing streak following a one run loss in Game 1 of this series. The Chicago offense has been terrible this season with a .211 team average as they have scored 32 and on 60 total hits. The Chicago pitching has been terrible as well with a 4.02 ERA through 10 games played. Stay in the action with our MLB Picks.

Andrew Benintendi leads the Chicago White Sox this season with a .290 batting average, two home runs, and six RBI's. Brooks Baldwin has come up big for Chicago as well this season with a .250 batting average. Korey Lee has a .385 batting average but has played in just eight games this season.

The Cleveland Guardians remain at home Wednesday two games below .500 on the year following their winning Game 1 of this series to end a 2 game losing streak. Offensively Cleveland has been a bottom feeder in the league with a .221 team average. Cleveland has scored 34 runs on 64 hits to go along with thirteen home runs this season. Cleveland pitching is one of the worst units in baseball with a 5.09 ERA despite giving up only one run in Game 1 of this set.

Steven Kwan leads the Cleveland offense  this season with a .316 batting average. Carlos Santana has been heavy as well for the Cleveland offense with a .289 batting average. Jose Ramirez has a .310 batting average to go along with the team leading four home runs this season. Kyle Manzardo has a .242 batting average leads Cleveland with nine RBI's this year.

White Sox vs Guardians Pick Analysis

Both teams have struggle a ton this year but Cleveland will have the edge in this game. Look for the Guardians to overpower a terrible Chicago team Wednesday leading to the win. Take the Guardians to do the job as they get the home win and cover. Final Score Prediction, Cleveland Guardians win and over 6-1.

Our Free MLB Pick for Cleveland Guardians vs Chicago White Sox

Cleveland Guardians -1.5