White Sox vs Reds Picks and Prediction – 5/14/2025

The Chicago White Sox play the second game of a three-game series on the road Wednesday versus the Cincinnati Reds. Chicago is 12-29 following its 4-2 win over the Miami Marlins on Sunday. Tim Elko hit a three-run homer for Chicago. The White Sox won two out of three from the Marlins, but the White Sox are last in the American League Central, 14 ½ games behind first place. Keep up to date with all the MLB action with our expert MLB picks.

Lenya Sosa is batting .257 to lead Chicago and has a team high of 36 hits. Andrew Benintendi is the leader in home runs with five, while Andrew Vaughn is the leader in RBI with 17, and Miguel Vargas is the leader in on-base percentage at .312. On Wednesday, the Chicago White Sox will send Davis Martin to the mound. The right-hander is 1-4 with a 4.01 ERA, 28 Ks, and 12 BBs.

The Cincinnati Reds are 20-22 following a 6-0 loss to the Houston Astros on Sunday. In eight innings, Cincinnati hitters were struck out 11 times by Houston starter Ronel Blanco. Cincinnati has lost three of the last four and seven of the last nine. The Reds are tied for third in the National League Central with the Milwaukee Brewers, four games behind the first-place Chicago Cubs.

Gavin Lux is batting .282 with a .377 on-base percentage, to lead Cincinnati in both. Elly De La Cruz is the leader in home runs with six and RBI with 29, while TJ Friedl is the leader in hits with 43. Cincinnati is batting .238 with a .378 slugging percentage. On Wednesday, Cincinnati will send Nick Lodolo to the mound. The left-hander is 3-3 with a 3.23 ERA, 38 Ks, and 7 BBs.

Cincinnati will win at home on Wednesday, but the play here is OVER. The OVER has cashed in four of the last six head-to-heads between the White Sox and Reds and in five of the Reds’ last seven vs an AL opponent. Chicago White Sox starter Davis Martin has been hit hard in two consecutive outings, allowing seven runs on 15 hits across 9.1 innings. Cincinnati starter Nick Lodolo has allowed eight runs on nine hits across 11.1 innings over his last two outings. Final Score Prediction, Cincinnati Reds win but our best play is OVER 7-5.