White Sox vs Red Sox Picks and Prediction – 4/19/2025

The Chicago White Sox (4–14) continue their series against the Boston Red Sox (10–10) at Fenway Park on Saturday, April 19. First pitch is scheduled for 4:10 PM ET, with coverage on NESN. Boston aims to build momentum after a recent series win, while Chicago seeks to snap a four-game losing streak. ​Get in on the action with our free MLB picks.

The White Sox have struggled this season, particularly on the road, where they hold a 0–6 record. Offensively, they average 3.0 runs per game with a team batting average of .196. Andrew Benintendi leads the team with a .273 average and two home runs, while Lenyn Sosa contributes a .281 average. ​

On the mound, right-hander Shane Smith is slated to start. Smith has a 0–1 record with a 2.04 ERA and a 0.91 WHIP over 17.2 innings, allowing nine hits and striking out 12 batters. ​

The Red Sox have been more consistent, especially at home with a 4–3 record. They average 4.3 runs per game and hold a team batting average of .247. Third baseman Alex Bregman leads the offense with a .321 average, four home runs, and 16 RBIs. ​

Left-hander Garrett Crochet is expected to start for Boston. Crochet boasts a 2–1 record with a 1.38 ERA and a 0.88 WHIP over 26 innings, striking out 28 batters.

Boston is the clear side to win here, although it is difficult to back them at the price. Shane Smith has actually been dealing for Chicago, and with Crochet against his old team, this should be a bit of a pitcher's duel. We will be taking the Under. Prediction: Red Sox win 3-2.