White Sox vs Orioles Picks and Prediction – 6/1/2025

Beautiful Camden Yards will play host to a Sunday afternoon MLB clash between the Chicago White Sox and the Baltimore Orioles. Be ready for the baseball season with all of our MLB predictions. The White Sox (18-40) have dropped 25 of their first 31 road games and own the worst overall record in the American League. On Saturday, Chicago batters went 2-for-11 with runners in scoring position and left 12 men on base during a 4-2 road loss against Baltimore. 

Thirty-two year old righty Adrian Houser (1-0 0.00 ERA) will make his third start of the year for the White Sox. Last time out, Houser fired six shutout frames and fanned six batters during a 2-1 road loss against the New York Mets. 

The Baltimore Orioles have won six of their last ten games and are trying to climb out of the AL East Division basement. During yesterday’s home victory, Baltimore 2B Jackson Holliday led off with seventh home run of the year. OF Jorge Mateo added a two-run shot for the Orioles (21-36), who improved to 11-17 at home.  

Forty-one year old righty Charlie Morton (1-7 7.09 ERA) is trying to regain his form for the Orioles. In his last start, Morton (6 IP) allowed two runs and struck out five batters during a 5-2 home victory versus St. Louis. 

Baltimore 1B Ryan Mountcastle has landed on the 10-day injured list with a right hamstring strain. Through 58 games, Chicago ranks 29th in OPS and 26th in runs scored. For the season, Baltimore ranks 22nd in OPS and 25th in runs scored. Take the over. Final Score Prediction, Baltimore Orioles win 7-4.