White Sox vs Orioles Picks and Prediction – 5/31/2025

By: Eddie Kline |

Last Updated: 05/30/2025 at 9:24 PM ET

Chicago White Sox at Baltimore Orioles 05/31/25 - MLB Picks & Predictions
Game Start: 5/31/2025, 8:05 PM UTC
Latest Odds: BAL -190 ; O/U 9

White Sox vs Orioles Prediction

The two worst teams in the American League will square off on Saturday afternoon, when the Chicago White Sox battle the Baltimore Orioles from Camden Yards. Be ready for the baseball season with all of our MLB predictions. The White Sox (18-39) have dropped 24 of their first 30 road games and are a dismal 19 games out of first place in the AL Central Division. Last night, Chicago OF Andrew Benintendi’s ninth-inning RBI double was not enough during a 2-1 road loss against Baltimore. 

Twenty-eight year old righty Davis Martin (2-5 3.45 ERA) will take the mound for the White Sox in this matchup. In his last start, Martin (6 IP) gave up four hits and two runs during a 5-4 home loss versus Texas. 

The Baltimore Orioles have split their previous ten games and are trying to climb out of the AL East Division cellar. During Friday’s home victory, Baltimore SS Gunnar Henderson and 1B Ryan Mountcastle went a combined 4-for-7 with two runs scored. SP Zach Eflin (4-2) tossed seven shutout innings and struck out six batters to earn the win for the Orioles (20-36), who improved to 10-17 at home. 

The Orioles will counter with twenty-nine year old righty Dean Kremer (4-5 5.02 ERA) on Saturday. Last time out, Kremer scattered seven hits across five plus shutout frames during a 5-1 road victory against Boston. 

White Sox vs Orioles Pick Analysis

Baltimore 1B Ryan Mountcastle was removed from Friday’s game with hamstring tightness and is listed as day-to-day. Through 57 games, Chicago ranks 28th in OPS and 26th in runs scored. For the season, Baltimore ranks 20th in OPS and 25th in runs scored. Take the over. Final Score Prediction, Baltimore Orioles win 6-5.

Our Free MLB Pick for Baltimore Orioles vs Chicago White Sox

OVER 9