Cubs vs Nationals Picks and Prediction – 6/3/2025

In Tuesday night MLB action, the Chicago Cubs will invade the nation’s capital to face the Washington Nationals. Be ready for the baseball season with all of our MLB predictions. The Cubs (37-22) have won eight of their previous ten games and hold a four-game lead over St. Louis for first place in the NL Central Division. On Sunday, OF Pete Crow-Armstrong went 3-for-4 three runs scored to spark Chicago to a 7-3 home victory versus Cincinnati. 

Rookie right-hander Cade Horton (2-0 3.98 ERA) will make his fourth career major league start for the Cubs. Last time out, Horton (6 IP) allowed two runs and struck out six batters during a 4-3 home victory versus Colorado. 

The Washington Nationals are a game below .500 at home and are sitting in third place in the NL East Division standings. On Sunday, Washington batters went 1-for-8 with runners in scoring position and struck out 13 times during a 3-1 road loss against Arizona. SP Mitchell Parker (4-5) gave up three runs in five innings and took the loss for the Nationals, who fell to 28-31 on the year. 

Washington manager Dave Martinez will turn to veteran right-hander Trevor Williams (3-5 5.69 ERA) in the series opener. In his last start, Williams fired six shutout frames during a 9-0 road victory against Seattle. 

Washington OF Dylan Crews is currently on the 10-day injured list with a lower back injury. Through 59 games, Chicago ranks 3rd in OPS and 2nd in runs scored. For the season, Washington ranks 15th in OPS and 11th in runs scored. Take the Nationals to win at home. Final Score Prediction, Washington Nationals win 6-3.