Cubs vs Nationals Picks and Prediction – 6/4/2025

The Chicago Cubs play the second game of a three-game series on the road Wednesday versus the Washington Nationals. Chicago is 37-22 following its 7-3 victory over the Cincinnati Reds on Sunday. Chicago has won two straight and six of the last seven. The Cubs lead the National League Central by four games over the St Louis Cardinals. Keep up to date with all the MLB action with our expert MLB picks.

Nico Hoerner is batting .301 with 65 hits to lead Chicago in both categories. Pete Crow-Armstrong is the leader in home runs with 15, and Seiya Suzuki is the leader in RBI with 52. Kyle Tucker leads in on-base percentage at .394. On Wednesday, the Chicago Cubs will send Matthew Boyd to the mound. The left-hander is 5-2 with a 3.08 ERA, 64 Ks, and 15 BBs.

The Washington Nationals dropped to 28-31 following Sunday’s 3-1 loss to the Arizona Diamondbacks, snapping a four-game winning streak for the Nationals. Washington is 11th in runs scored and 19th in batting average, while the Nationals are a disappointing 26th in ERA. Washington is 3rd in the National League East, 9 ½ games behind the first-place New York Mets.

James Wood is batting .286 with 16 home runs, 44 RBI, 64 hits, and an on-base percentage of .385 to lead Washington in each of the five categories. Josh Bell is second in home runs with nine. Washington is batting .244 with a .313 slugging percentage. On Wednesday, Washington will send MacKenzie Gore to the mound. The left-hander is 2-5 with a 3.16 ERA, 101 Ks, and 21 BBs.

Washington will win at home on Wednesday, but the play here is UNDER. The UNDER has cashed in four of Chicago's last six, six of Washington's last seven at home, and four in the last five between Chicago and Washington. Chicago starter Matthew Boyd is coming off a strong outing in which the left-hander allowed no runs on four hits across 6 innings. Washington starter MacKenzie Gore has had three consecutive strong outings, allowing three runs on 16 hits across 15.2 innings. Final Score Prediction: Washington Nationals win but our best play is UNDER 4-2.