Cubs vs Cardinals Picks and Prediction – 6/26/2025

The Chicago Cubs stay on the road Friday with their final game of a four-game set in Saint Louis against the Cardinals. Chicago has 46 wins and 33 losses on the year having dropped for the last five including three in a row overall. Offensively Chicago has a .255 batting average as they have scored 426 runs on 697 hits this season. The Chicago pitching has been solid enough this season with a 3.95 team ERA. Stay in the loop with our MLB Picks.

Nico Hoerner leads the Chicago offense this season with a .294 batting average and 85 hits on the year. Pete Crow-Armstrong has a .273 batting average, and is tied for the team lead with 21 home runs this season. Say a Suzuki has a .262 batting average to go along with 21 home runs and a team leading 67 RBIs this year.

The Saint Louis Cardinals stay on their home floor Thursday with 44 wins and 36 losses this season having won for the last five including both games in this series thus far. Offensively St. Louis solid this season with the .256 batting average as they have scored 380 two runs on 697 hits. The Saint Louis pitching has held true as well this season with a 3.9 four team ERA and the Cardinals have allowed nine total runs across two games in this series.

Brendan Donovan leads the Saint Louis offense this season with a .310 batting average and 87 hits on the year. Nolan Arenado has a .247 batting average and Masyn Wynn has a .256 batting average this season. Lars Nootbar has a .230 batting average and leads Saint Louis with eleven home runs. Willson Contreras has a .248 batting average to go along with a team leading fifty RBIs through 75 games played.

The Cubs are the far better team in this game and it will show from the jump on Thursday. Look for Chicago to control this game start to finish against the Cardinals. Chicago has the deeper more talented team and the better arm on the bump. Take Chicago Thursday to get the road win. Final Score Prediction, Chicago Cubs win 6-1.