Cubs vs Phillies Picks and Prediction – 6/10/2025

In Tuesday night MLB action, the Chicago Cubs and the Philadelphia Phillies will continue their series from Citizens Bank Park. Be ready for the baseball season with all of our MLB predictions. The Cubs (40-26) are five games above .500 on the road and hold a 3.5 game lead over St. Louis for the top spot in the NL Central Division. Last night, Chicago outfielders Ian Happ and Kyle Tucker each homered during a 4-3 road loss in 11 innings. 

Thirty-four year old righty Colin Rea (4-2 3.59 ERA) will head to the hill for the Cubs in this contest. Last time out, Rea fired five plus shutout frames and did not strike out a batter during a 7-1 road triumph against Washington.

The Philadelphia Phillies have won 20 of their first 32 home games and trail NL East Division leading New York by four games. During Monday’s home victory, Philadelphia C J.T. Realmuto tied the game in the final frame with an RBI single and scored the winning run on a Brandon Marsh base knock. 3B Otto Kemp went 3-for-5 with a run scored for the Phillies, who improved to 38-28 overall.

Rookie right-hander Mick Abel (1-0 0.79 ERA) will make his third career major league start for the Phillies. Through 11 plus innings, Abel has registered 11 strikeouts without allowing a walk or a home run.

Philadelphia 1B Bryce Harper has landed on the 10-day injured list with right wrist inflammation. Through 66 games, Chicago ranks 3rd in OPS and 2nd in runs scored. For the season, Philadelphia ranks 10th in OPS and 10th in runs scored. Take the Cubs to win on the road. Final Score Prediction, Chicago Cubs win 6-4.