Cubs vs Mets Picks and Prediction – 5/10/2025

By: Ricky MacKenzie |

Last Updated: 05/09/2025 at 11:33 PM ET

Chicago Cubs at New York Mets 05/10/25 - MLB Picks & Predictions
Game Start: 5/10/2025, 11:15 PM UTC
Latest Odds: NYM -155 ; O/U 9

Cubs vs Mets Prediction

This Saturday, Tylor Megill and the Chicago Cubs head to Citi Field to take on Francisco Lindor and the New York Mets in a compelling National League matchup. Get our free MLB Picks all season long! The Cubs, now 22-16, are coming off a 3-1 loss to the Giants on Wednesday and will look to regroup as they open a new series.

Megill has shown flashes of potential this season but has struggled with efficiency and command at times. He’ll need to avoid falling behind in counts against a Mets lineup that’s patient and capable of punishing mistakes. A strong start will be critical to keep Chicago in the game.

The Mets, now 24-14, are riding high after a 7-1 win over the Diamondbacks. Lindor continues to lead by example, producing at the plate and anchoring the infield. The Mets’ offense has been explosive lately, and they’ll look to stay hot as they continue their push near the top of the division.

Chicago must generate more consistent offense to support Megill, especially early in the count. New York will look to stay aggressive and wear down Megill while relying on their bullpen to secure a lead if needed. Run prevention and timely hitting will likely decide this game.

Cubs vs Mets Pick Analysis

With Lindor pacing a confident lineup and the Mets playing with momentum, New York has the edge at home. Megill will need a near-perfect outing to steal a win, but the Mets’ balance on both sides gives them the upper hand. Take the Mets to win and to cover the run line. Final Score Prediction, New York Mets win 6-3.

Our Free MLB Pick for New York Mets vs Chicago Cubs

New York Mets -1.5