Cubs vs Brewers Picks and Prediction – 5/3/2025

The Cubs roll into American Family Field on Saturday with a 19-13 record and a 10-6 mark on the road. Milwaukee sits at 16-16 and boasts a solid 9-4 home record. Chicago is coming off a convincing 8-3 win in Pittsburgh, while the Brewers just got blanked 8-0 by the White Sox. Saturday's pitching matchup features righty Jameson Taillon (1-1, 4.01 ERA) for the Cubs against lefty José Quintana (4-0, 1.14 ERA) for the Brewers. Elevate your MLB game with our top-notch MLB picks.

Chicago has looked sharp over the past week, winning three of its last five and scoring eight or more in two of those. The lineup is led by Seiya Suzuki, who’s putting together a strong start with 9 home runs, a .295 average, and 28 RBIs. The Cubs' offense is clicking, averaging .264 at the plate with 46 homers and 192 runs scored. 

The Cubs hold a 3.98 team ERA and are limiting opponents to a .247 batting average. Taillon has been steady in his starts, with a 1.10 WHIP and just 30 hits allowed over 33.2 innings. He’ll look to limit the long ball, having already given up five home runs. Injuries are mostly in the bullpen, with Ryan Brasier and Tyson Miller both out, and Javier Assad still weeks away from returning. Even with those arms missing, Chicago has enough to compete on the mound.

Milwaukee had been gaining momentum with three straight wins before the 8-0 loss to the White Sox. The offense has been inconsistent, putting up just 159 total runs this season. Jackson Chourio leads the way with six homers and 24 RBIs, and Brice Turang has been steady with a .311 average. Still, a .244 team average and .368 slugging show this group lacks the pop needed to win shootouts.

Defensively, Milwaukee posts a 4.23 ERA and allows a .241 average to opponents. Quintana has been fantastic, going 4-0 with a 1.14 ERA and only one homer allowed in 23.2 innings. He’s been a huge asset in keeping games close. The Brewers are banged up in the rotation with Woodruff and Civale on the IL.

The Cubs have the better offense by a wide margin—46 homers to Milwaukee’s 27 and a .264 team average to Milwaukee’s .244. Even against a red-hot José Quintana, the deep Chicago lineup can produce runs. Taillon has quietly held things together, and Milwaukee’s inconsistency at the plate could show again. Final Score Prediction: Chicago Cubs win 4-3.