Cubs vs Tigers Picks and Prediction – 6/6/2025

The Chicago Cubs open a three-game series on the road Friday versus the Detroit Tigers. Chicago is 38-23 following Wednesday’s 2-0 loss to the Washington Nationals. The loss snapped a three-game winning streak for Chicago, but the Cubs have won seven of the last nine. Chicago leads the National League Central by 4 ½ games over the St Louis Cardinals. Keep up to date with all the MLB action with our MLB picks.

Nico Hoerner is batting .296 with 66 hits to lead Chicago in both categories. Pete Crow-Armstrong is the leader in home runs with 15, and Seiya Suzuki is the leader in RBI with 53. Kyle Tucker is the leader in on-base percentage at .393. On Friday, the Chicago Cubs will send Ben Brown to the mound. The right-hander is 3-3 with a 5.72 ERA, 71 Ks, and 19 BBs. 

The Detroit Tigers improved to 41-22 following Wednesday’s 5-4 victory over the Chicago White Sox. Colt Keith hit an RBI double to break a tie in the 8th inning and help lead the Major League-leading Tigers to the win. Detroit has won eight of the last 10. Detroit is first in the American League Central, six games ahead of the second-place Minnesota Twins.

Riley Greene is batting .283 with 42 RBI and 67 hits to lead Detroit in the three categories. Spencer Torkelson is the leader in home runs with 14, and Gleyber Torres is the leader in on-base percentage at .383. Detroit is batting .251 with a .410 slugging percentage. On Friday, Detroit will send Tarik Skubal to the mound. The left-hander is 5-2 with a 2.26 ERA, 99 Ks, and 7 BBs.

The Detroit Tigers will win at home on Friday when hosting the Chicago Cubs, but the play here is UNDER. The UNDER has cashed in four of Chicago's last six. Chicago starter Ben Brown is coming off a strong outing in which the right-hander allowed no runs on one hit across six innings, while Detroit starter Tarik Skubal has allowed no runs on four hits across the last 16 innings. The UNDER has cashed in each of Skubal’s last two starts. Final Score Prediction: Detroit Tigers win but our best play is UNDER 3-2.