Cubs vs Reds Picks and Prediction – 5/24/2025

The Chicago Cubs play the second game of a three-game series on the road Saturday versus the Cincinnati Reds. Chicago is 30-20 following its 2-1 victory over the Miami Marlins on Wednesday. Kyle Tucker homered for the second straight game to help lead Chicago to the victory. The Cubs have won five of the last six and lead the National League Central by three games. Keep up to date with all the MLB action with our MLB picks.

Nico Hoerner is batting .287 to lead Chicago, while Kyle Tucker is the leader in home runs with 12 and on-base percentage at .387. Seiya Suzuki is the leader in RBI with 43, and Pete Crow-Armstrong is the leader in hits with 55. On Saturday, the Chicago Cubs will send Colin Rea to the mound. The right-hander is 3-0 with a 2.38 ERA, 32 Ks, and 11 BBs.

The Cincinnati Reds dropped to 25-26 following Wednesday’s 3-1 loss to the Pittsburgh Pirates. Cincinnati lost two out of three on the road to Pittsburgh. Before two straight losses to the Pirates, Cincinnati had won five straight. The Reds are tied for third in the National League Central with Milwaukee, 5 ½ games behind the first-place Cubs.

Gavin Lux is batting .292 with an on-base percentage of .377 to lead Cincinnati in both categories. Elly De La Cruz is the leader in home runs with eight and RBI with 33, while TJ Friedl is the leader in hits with 49. Cincinnati has a .241 batting average and .391 slugging percentage. On Saturday, Cincinnati will send Andrew Abbott to the mound. The left-hander is 3-0 with a 1.80 ERA, 43 Ks, and 15 BBs.

The UNDER has cashed in seven of Chicago's last nine versus Cincinnati, in each of Cincinnati's last seven played at home, and in each of Cincinnati's last 10 overall. Chicago starter Colin Rea has had two consecutive solid outings, allowing three runs on 10 hits across 12 innings. Cincinnati starter Anthony Abbott has had four consecutive strong outings, allowing one run on 15 hits across 20 innings, with the total cashing UNDER in three of the four. Final Score Prediction: Cincinnati Reds win but our best play is UNDER 4-2.