Cubs vs Diamondbacks Picks and Prediction – 3/30/2025

On Saturday, the Chicago Cubs (1-2) face off against the Arizona Diamondbacks (0-1) at Chase Field in Phoenix, Arizona. Keep up to date with all the MLB action, with our expert MLB picks.

Arizona comes into this matchup having lost to the Cubs on Opening Day, 10-6, before their second game against them. In that matchup, Eugenio Suarez hit safely once in three at-bats, contributing two runs, a home run, and an RBI. For the Diamondbacks, Geraldo Perdomo also had one hit in three at-bats, driving in two runs. Ketel Marte managed two hits in five at-bats and crossed the plate twice for Arizona. On the mound, pitcher Zac Gallen pitched four innings, surrendering four earned runs, four hits, and issuing four walks, while striking out four batters. The Diamondbacks are eager to bounce back and secure a win against the Cubs on their home field. Last season, they averaged 5.5 runs per game.

Chicago enters this game having dropped two of their first three games. In Thursday's 10-6 triumph over Arizona, Miguel Amaya played a pivotal role for Chicago by going 2-for-5 at the plate and contributing five RBIs. Ian Happ also shined with a 2-for-5 performance, bringing in three runs, scoring twice, and hitting a home run. Matt Shaw added to the offense by going 1-for-4 and driving in three runs. On the mound, Justin Steele pitched five innings, during which he gave up three earned runs, allowed six hits, and issued one walk. As the Cubs head to Phoenix, they aim to maintain their winning streak. Last season, the Cubs averaged 4.5 runs per game.

Last season, the Diamondbacks were the top team in the league when it came to scoring runs per game. Their knack for putting points on the board was particularly evident in home games. This was showcased in their Opening Day matchup against the Cubs, where they tallied six runs. On the mound for Chicago was Shota Imanaga, who boasted an impressive 15-3 record with a 2.91 ERA last year. In contrast, Arizona's starting pitcher, Brandon Pfaadt, had a more challenging season, finishing with an 11-10 record and a 4.71 ERA. Imanaga aims to continue his strong performance from last season and secure a road win. Final Score Prediction, Arizona Diamondbacks win 5-3.