Red Sox vs Mariners Picks and Prediction – 6/18/2025

By: Ricky MacKenzie |

Last Updated: 06/17/2025 at 12:10 AM ET

Boston Red Sox at Seattle Mariners 06/17/25 - MLB Picks & Predictions
Game Start: 6/18/2025, 1:40 AM UTC
Latest Odds: SEA -185; O/U 7.5

Red Sox vs Mariners Prediction

This Tuesday, Walker Buehler takes the mound for the Boston Red Sox against the Mariners following a sharp 2-0 shutout over the Yankees. Buehler continues rounding into form after injury setbacks, showing flashes of dominance with his fastball and slider. Get our free MLB Picks all season long! Buehler will aim to neutralize a Seattle lineup that can be streaky but dangerous.

Boston’s offense has relied on contact and smart baserunning. Jarren Duran remains the table-setter, while Rafael Devers has just been traded to the Giants. The Red Sox will need production from the middle of the lineup to support Buehler, especially against a Mariners pitching staff that has been one of the most efficient in baseball.

Bryan Woo will counter for the Mariners after a brilliant 6-0 victory over the Guardians. Woo doesn’t walk many and pounds the zone with confidence. His pitch sequencing keeps hitters guessing, and if his command holds, he’s capable of shutting down a Red Sox team that doesn’t have a deep bench.

Seattle’s bats have been inconsistent but show flashes, especially with Julio Rodríguez starting to heat up. The bullpen, anchored by Andrés Muñoz, is rested and ready. If Seattle scores early, the pitching staff could carry the rest. Expect tight defense and a low-scoring affair between these playoff hopefuls.

Red Sox vs Mariners Pick Analysis

This game has all the makings of a pitchers’ duel. Buehler and Woo should keep runs at a premium, but Seattle’s bullpen advantage and home field tilt the edge in their favor. In a tense, low-scoring battle, the Mariners come through in the clutch. Final score prediction, Seattle Mariners win 2-1.

Our Free MLB Pick for Seattle Mariners vs Boston Red Sox

Seattle Mariners -185