Red Sox vs Phillies Picks and Prediction – 7/22/2025

Citizens Bank Park will play host to a Tuesday night MLB interleague clash between the Boston Red Sox and the Philadelphia Phillies. Be ready for the baseball season with all of our MLB predictions. The Red Sox (54-48) have won seven of their last ten games and hold a one-game lead over Tampa Bay for the final AL Wild Card spot. Last night, Boston batters went 1-for-10 with runners in scoring position during a 3-2 road loss against Boston in ten innings. 

Twenty-five year old righty Richard Fitts (1-3 4.28 ERA) will head to the hill for the Red Sox in this contest. Last time out, Fitts (5.2 IP) allowed two runs and struck out six batters during a 9-3 home victory versus lowly Colorado. 

The Philadelphia Phillies have won 32 of their first 50 home games and are clinging to a one-game lead over New York for the top spot in the NL East Division. During Monday’s home victory, Philadelphia walked it off on a catcher’s interference that allowed Brandon Marsh to score. SP Zack Wheeler (6 IP) retired ten batters by strikes and did not factor in the decision for the Phillies (57-43).

Philadelphia manager Rob Thomson will counter with left-hander Cristopher Sanchez (8-2 2.50 ERA) on Tuesday. Through 115 innings of work, Sanchez has fanned 122 batters and sports a solid 1.14 WHIP.

Philadelphia 3B Alec Bohm has been placed on the 10-day injured list with a fractured left rib and will miss this series. Through 102 games, Boston ranks 5th in OPS and 5th in runs scored. For the season, Philadelphia ranks 10th in OPS and 12th in runs scored. Take the over. Final Score Prediction, Philadelphia Phillies win 6-5.